Branched-chain-2-oxoacid decarboxylase
| branched-chain-2-oxoacid decarboxylase | |||||||
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| Identifiers | |||||||
| EC number | 4.1.1.72 | ||||||
| CAS number | 63653-19-0 | ||||||
| Databases | |||||||
| IntEnz | IntEnz view | ||||||
| BRENDA | BRENDA entry | ||||||
| ExPASy | NiceZyme view | ||||||
| KEGG | KEGG entry | ||||||
| MetaCyc | metabolic pathway | ||||||
| PRIAM | profile | ||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||
| Gene Ontology | AmiGO / EGO | ||||||
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In enzymology, a branched-chain-2-oxoacid decarboxylase (EC 4.1.1.72) is an enzyme that catalyzes the chemical reaction
- (3S)-3-methyl-2-oxopentanoate
2-methylbutanal + CO2
Hence, this enzyme has one substrate, (3S)-3-methyl-2-oxopentanoate, and two products, 2-methylbutanal and CO2.
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (3S)-3-methyl-2-oxopentanoate carboxy-lyase (2-methylbutanal-forming). Other names in common use include branched-chain oxo acid decarboxylase, branched-chain alpha-keto acid decarboxylase, branched-chain keto acid decarboxylase, BCKA, and (3S)-3-methyl-2-oxopentanoate carboxy-lyase.